Dr. David Barker first popularized the concept of fetal origins of adult disease (FOAD). Since its inception, FOAD has received considerable attention. The FOAD hypothesis holds that events during early development have a profound impact on one’s risk for development of future adult disease. Low Cited by: 356. Aug 22, 2012 · The concept of a fetal origin of adult disease have been extended well beyond coronary heart disease and being a risk factor for coronary heart disease, and now includes investigations of the development of the central nervous system, early origins of adult mental health 21 and cognitive function. 22 Although the FOAD-hypothesis has been Cited by: 78.
disease incidence (coronary heart disease mortality, non-insulin-dependent diabetes) or risk factors for those diseases (hypertension, glucose intolerance, hyperlipidemia) (1,3). The ‘Fetal Origin of Adult Disease (FOAD)’ Hypothesis Barker hypothesized that the associations between small size at birth or during infancy and later CVD reflectCited by: 11. The thrifty phenotype hypothesis says that reduced fetal growth is strongly associated with a number of chronic conditions later in life. This increased susceptibility results from adaptations made by the fetus in an environment limited in its supply of nutrients. The thrifty phenotype is a component of the fetal origins hypothesis.These chronic conditions include coronary heart disease.
Fetal Origin of Adult Disease Related Articles. The Dangerous Effects of Trans Fats in Pregnancy. Written by Eleni Roumeliotou. Accumulating science reveals we should worry about the impact of trans-fats on the brain of unborn children and the next generation in general. Print Options. Feb 17, 2001 · He postulated that impaired fetal growth might have predisposed the survivors to heart disease in later life. The first world congress on the fetal origins of adult disease in Mumbai earlier this month provided an opportunity to assess the state of the hypothesis and consider its implications for future research and policy.Cited by: 309.
Dr. David Barker first popularized the concept of fetal origins of adult disease (FOAD). Since its inception, FOAD has received considerable attention. The FOAD hypothesis holds that events during early development have a profound impact on one's risk for development of future adult disease.Cited by: 356. Evidence for fetal origins of adult disease. The evidence that does exist for pre-adult influences on cardiovascular disease, extending back from adolescence through childhood, into infancy and ultimately fetal life, has been recently reviewed elsewhere (Leon and Ben-Shlomo, 1997).